Methoxyvone™ initiates protein synthesis and this effect triggers positive nitrogen stability. Theorized to help in building up of protein and thus builds up skeletal muscle mass.
Attention: These products are not anabolic steriods and all claims are theories. LG Sciences’ products will only assist you in reaching your fitness goals. Muscle and weight gain are the result of hard exercise and proper diet, supplements are not a replacement.
5-methyl-7-methoxy-isoflavone (U.S. patent 4,163,746)
Methoxyvone™ aka the “Anabolic Silver Bullet” is an oral anabolic agent that can significantly affect protein metabolism in the body. Methoxyvone™ initiates protein synthesis and this effect triggers positive nitrogen stability helping in building up of protein and thus builds up skeletal muscle mass. The search for a supplement that would produce the highly anabolic and sought-after effects of faster muscle growth, recovery, and lean muscle increases, yet avoid the androgenic steroid-like side effects has been an impossible task? Many of the flavones studied over the past several decades would show excellent results in animals and even some in humans via non oral routes. This dilemma has been overcome with LG Sciences Cyclosome™ Technology that cause Methoxyvone™ to have a 20 fold increase versus regular encapsulated 5-methyl-7-methoxy-isoflavone. There have been several products on the market in the past that only got mediocre results. That is why the only catch with this compound is bioavailability. Unfortunately, without an effective system like LG’s Cyclosome™ Technology, Methoxyvone™ is not well absorbed and therefore could be rendered ineffective. Please be sure that any isoflavone or 5-methyl-7-methoxy-isoflavone product you purchase has a scientifically sound method to drastically increase its bioavailability.
Several of the flavones that held promise were originally discovered and patented by a Hungarian company who held a patent that did not expire until 1997. Two of these compounds were 5-methyl-7-methoxy-isoflavone (U.S. patent 4,163,746) and 7-Isopropoxyisoflavone have been shown to increase protein synthesis and increase lean mass, but they also reduced body fat, promoted endurance, an increased state of vitality, and increased the body’s ability to use oxygen! In other words, these are the definition of the ideal anabolic supplements… Scientific studies give evidence to support these results. In a nutshell, methoxyisoflavone and ipriflavone are non-hormonal anabolic / anti-catabolic compounds. These powerful flavones have been shown to decrease cortisol levels, increase protein synthesis, and improve overall recovery from exercise.
Phytomedicines, complex chemical mixtures prepared from plants, have been used in medicine since ancient times and continue to have widespread popular use. Most of the bioactive constituents of herbal drugs are water soluble molecules However, water soluble phyto-constituents like many flavonoids are poorly absorbed either due to their multiple ring large size molecules which cannot be absorbed by simple diffusion, or due to their poor miscibility with oils and other lipids, severely limiting their ability to pass across the lipid-rich outer membranes of the enterocytes of the small intestine. Water-soluble constituent molecules (mainly polyphenols) can be converted into lipid-compatible molecular complexes, which are called Cyclosome™.
Cyclosome™ are more bioavailable as compared to simple herbal extracts owing to their enhanced capacity to cross the lipid rich bio membranes and finally reaching the blood. Phospholipids are complex molecules that are used in all known life forms to make cell membranes. They are cell membrane building blocks, making up the matrix into which fit a large variety of proteins that are enzymes, transport proteins, receptors, and other biological energy converters. In humans and other higher animals the phospholipids are also employed as natural digestive aids and as carriers for both fat-miscible and water-miscible nutrients. They are miscible both in water and in oil/lipid environments, and are well absorbed orally. Phospholipids are small lipid molecules in which the glycerol is bonded only to two fatty acids, instead of three as in triglycerides, with the remaining site occupied by a phosphate group. The phospholipid mainly employed to make cyclosomes, is phosphatidylcholine, derived from soybean.
In order to fully understand the power of Methoxyvone™, however; we must start with the first anabolic flavone compound to make big waves: 7-Isopropoxyisoflavone or Ipriflavone. The research was aimed toward finding a nutrient partitioning agent able to transport much needed nutrients away from fat (adipose) tissue and toward muscle (proteinaceous) tissue. While most companies were pouring millions of dollars into new more effective anabolic steroids, one company in Hungary, named Chinoin, decided to look for a non-steroidal compound that would have the positive effects of Anabolics but without the negative characteristics. Chinoin (Hungarian pharmaceutical company), a leader in flavonoid research and knowledge, developed Ipriflavone in the early 1970’s. After over 10 years of research, they discovered Methoxyvone. Methoxyvone was the end result of Chinoin’s extensive research on anabolic isoflavones.
Said slightly in another way, Methoxyvone is three times more potent than ipriflavone in term of increasing lean body mass, decreasing adipose stores, increasing endurance, etc. Although developed in the last millennium, it is destined to become one of the best ergogens in this new millennium. LG’s excitement for this product stems not only from the published data on Methoxyvone but also based on the plethora of correspondence had with Chinoin. According to their research department, they performed a barrage of experiments to examine its anabolic potency. To give an idea of its capabilities, Methoxyvone was studied to see whether it could antagonize the catabolic effects of gluccocorticoids, i.e. cortisol. For those of you who don’t know already, gluccocortidoids are one of the most catabolic entities (especially relating to proteinaceous tissue such as muscle) in the human body. Although they do have some very important beneficial properties such as anti-inflammation, when it comes to gaining muscle and losing fat they are your worst nightmare. Gluccocorticoids are always in your body and they are always wreaking havoc. They are produced in the adrenal cortex, released into the blood and attach to various receptors in nearly every tissue in the body. Methoxyvone, on the other hand, almost completely antagonized cortisol’s effects at lower dosages and did a good job of attenuating them at higher dosages.
Studied during the same time period as Ipriflavone, Methoxyisoflavone’s scientific data definitely impressed the government to justify issuing a patent for it. As it turns out, Methoxyisoflavone is perhaps the most potent legal anabolic compound with no side effects. Some of the findings include:
Thus, a few years ago when I started researching these anabolic isoflavones, I was limited only to Iproflavone because of cost and availability. Although I was impressed with Ipriflavone I had my sights set on Methoxyvone.
Anabolic or anti-catabolic compounds are called nutrient partitioning agents. Normally, when you ingest calories a certain portion of them are used for immediate needs, others are partitioned off into fat stores, and still others are used to build proteinaceous tissues. A nutrient partitioning agent will take more of those calories and shuttle them into proteinaceous tissues. Therefore, a nutrient partitioning agent or anabolic compound will make you leaner and more muscular if your calorie intake remains the same but it won’t cause you to gain weight. To gain weight you must either consume more calories or slow down your metabolism. The great thing about taking an anabolic is that if you ingest more calories, it will cause a preferential increase in muscle mass.
DIRECTIONS: Take 2 tablets spread out during the day with at least 6 hours between doses. Do not exceed recommended dosage.
Serving Size: 1 Tablet
KEEP OUT OF REACH OF CHILDREN. NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 21 YEARS. Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of, prostate cancer, prostate enlargement, heart disease, low “good” cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over the counter drug. Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heart beat, dizziness, blurred vision, or other similar symptoms. Made in a facility that may process dairy, peanuts, tree nuts, wheat, fish, barley and shellfish. Do not use if governed by any body that prohibits hormone use.
LG Sciences is a pioneer in the Bodybuilding and Prohormone industry being one of the first companies to introduce many of the prohormones that have search entered the marketplace over the last decade. Researchers at LG Sciences recently developed a proprietary process called Cyclosome™ Technology. This one-of-a-kind technology brought to you by the leaders in Prohormones involves the entrapment of hydrophobic prohormones and other Testosterone boosting compounds in the form of water-soluble Prohormone–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to combine the relative advantages of CDs and liposomes into one system, namely Prohormone-in-CD-in-liposome systems called Cyclosome’s™. You can think of all this in terms of a ‘Trojan Horse,’ passing through the liver unharmed and intact. As opposed to being destroyed in the liver like all other hormonal products on the market, past and present. This new Cyclosome™ technology allows the ‘Trojan Horse’ to deliver prohormones and testosterone boosters to the systemic circulation by the intestinal lymphatic route, circumventing first-pass inactivation in the liver for the very first time. Almost all previous Oral capsules and tablets manufactured to increase testosterone — including Testosterone itself — are involved in the “first pass affect” which renders the active compounds virtually useless.
Cyclosome™ Technology — the most advanced liposomal delivery technology ever developed for bioavailability is the answer to getting poorly absorbed Testosterone boosting compounds and legal prohormones into the body so they can work ! The pharmaceutical industry has embraced this cutting-edge technology in recent years and now EpiAndro 50™ will be one of the first to utilize it in a testosterone booster and anabolic agent.
For Cyclosome™ preparation, an overall understanding of the interaction between CDs and lipid components of liposomes is necessary for this complex. LG Sciences has developed a Double-loading technique, which is a revolutionary strategy to prohormone release and increase prohormone-loading capacity. The Cyclosome™ approach can be useful in increasing prohormone solubility and vesicles stability, in controlling the in vivo fate of hydrophobic compounds and in avoiding burst release of prohormones from the vesicles. To obtain a stable Cyclosome™, the CDs should have a higher affinity to prohormone molecules compared with liposomal membrane lipids. Cyclosomes prepared by LG’s double-loading technique are the most advanced targeted prohormone delivery system ever developed because they have a fast onset action with prolonged prohormone release process and the significantly enhanced prohormone-loading capacity.