Green Coffee Bean Extract
Green Coffee Bean Extract – Natural Fat-Loss Aid & Anti-Oxidant
If you’re an avid coffee drinker, you may live by the motto: A cup a day keeps the fat away. After all, coffee contains caffeine – and caffeine has a long and trusted reputation as a mild stimulant weight-loss aid. As reported in a 2010 issue of the International Journal of Obesity, caffeine is a “tool for obesity management” as it has the potential to increase a person's base metabolic rate (the rate at which he or she expends energy at rest) by 4% or 5%.
However, caffeine isn’t the only ingredient that contributes to coffee’s metabolism-boosting effects. The actual green (or raw) coffee bean is a powerful fat-fighting agent in and of itself, containing high amounts of a key substance known as chlorogenic acid. Sound familiar? Chlorogenic acid has recently been highlighted on the Dr. Oz show based on studies supporting its role in boosting metabolism. In fact, several reports on both humans and animals have shown that green coffee bean extract (containing chlorogenic acid) holds great potential as an anti-obesity agent. Harnessing the power of this pure and natural bean, Labrada has introduced Green Coffee Bean Extract Fat-Loss Optimizer.
Another Reason to "Go Green"
Guzzling extra java is certainly a way to temporarily boost energy – but this won’t deliver the fat-loss results you could experience with Green Coffee Bean Extract. The key is in the green. Raw coffee beans are a major source of chlorogenic acid, but as soon as you put them through the roaster for commercial coffee preparation, you lose most of the "good stuff" – including the chlorogenic acid and other beneficial polyphenolic substances (not to mention the bean’s natural green color).
Green Coffee Bean Extract from Labrada is a natural powder extracted from unroasted coffee beans to ensure maximum potency and effectiveness. Taking Green Coffee Bean Extract in supplement form is also an easy alternative for people who don’t have the desire (or spare change) to drink multiple cups of coffee per day.
Let’s Talk Fat Loss
In contrast to caffeine – which is a stimulant that increases caloric expenditure and stimulates fat burning and weight loss – Green Coffee Bean Extract induces fat loss via non-stimulant mechanisms. While these mechanisms are outlined in further detail in our excellent "Digging Deeper into the science section below by Monica Mollica BSc and MSc.
1. Slowing the release of sugar into the bloodstream (especially after large meals)
2. Increasing the activity of your body’s fat-burning enzymes
3. Reducing triglyceride (fat) levels in the body
In a nutshell, Green Coffee Bean Extract is able to significantly lower fasting blood sugar levels and stop after-meal blood sugar surges in their tracks. This blood sugar regulation may contribute as a deterrent to long-term health problems (such as diabetes and heart disease). It also helps guard against extra body fat storage.
In a study analyzing the human consumption of 200 mg of green coffee bean extract per day, average weight loss results were 5.5 pounds (2.5 kg) in 12 weeks. Results were even more significant with higher daily doses; When up to 1,050 mg (350 mg three times daily) of the standardized green coffee bean extract were consumed, overweight individuals experienced a weight loss of nearly 18 pounds (8 kg) after 22 weeks. This higher dosage (complemented by diet and exercise), was well tolerated and did not cause any adverse side effects.
The Anti-Oxidant Advantage
Green Coffee Bean Extract has been reported to have antioxidant properties, similar to those of green tea and grape seed extract. Antioxidants, by nature, provide support against oxidative stress by helping to reduce free radicals in the body. In this way, Green Coffee Bean Extract is far more than a fat-loss aid – it’s a natural tool to help you feel your best and maintain overall health.
This article has just barely scratched the surface of what Green Coffee Bean Extract is capable of doing for people of all ages and body types. To learn more about the important role Green Coffee Bean Extract plays in regulating blood sugar levels, supporting fat loss, and preventing disease, please read our "Digging into the Science" section below by Monica Mollica BSc , MSc.
Digging Deeper Into The Science
In discussions about the health benefits of coffee drinking, the effects of coffee are often confused with those of caffeine. While it is true that many of the effects of coffee are caused by caffeine, coffee also has several interesting and beneficial non-caffeine related effects.
Chlorogenic acid in Green Coffee Bean - a key player
Coffee contains a myriad of biologically active substances, and recent research has identified chlorogenic acid as being one of them 1. Chlorogenic acid is present in highest amounts in the coffee bean and the seeds inside the coffee berry. Green (or raw) coffee is a major source of chlorogenic acid 2. Commercial preparation of coffee destroys a lot of the chlorogenic acid and other beneficial polyphenolic substances, but heavy coffee drinkers may still ingest from 0.5 to 1.0 g chlorogenic acid per day 3. Labrada Green Coffee Bean Extract (details)
Anti-obesity effects of Green Coffee Bean Extract
Several studies in both humans and animals have showed that green coffee bean extract holds great potential as an anti-obesity agent.
A study investigating the effect of green coffee bean extract on fat accumulation and body weight in mice demonstrated weight loss with a reduced abdominal (visceral) and hepatic fat content 4. This effect was attributed to activation of fat metabolism in the liver 4. Another study in obese mice fed a high-fat diet found that chlorogenic acid not only significantly lowered body weight, visceral fat mass and insulin levels, but also reduced triglyceride levels and cholesterol levels 5. In addition, it was found that chlorogenic acid also elevated adiponectin levels in the blood (more on this below) 5.
In a study on hamsters fed a high-fat it was found that chlorogenic acid beneficially affected both glucose and fat metabolism, as indicated by a significant reduction in levels of fasting blood triglycerides, free fatty acids, total cholesterol, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), glucose (FSG), and insulin 6. This study also found a reduction in live fat content6.
In humans, supplementation of 200 mg green coffee extract per day results in an average weight loss of (2.5 kg) in 12 weeks 7. Higher daily doses up to 1050 mg (350 mg three times daily) of the standardized green coffee bean extract (Svetol®) have induced a larger magnitude a weight loss of 8 kg in overweight individuals after 22 weeks, who also adhered to diet and exercise advice 7. The higher dose was well tolerated and did not cause any adverse effects 7.
Consume 2 capsules in the evening with food or as recommended by your health care professional.
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children. Protect from heat, light and moisture. Store at 15-30C or 59-86F.
How does it work?
In contrast to caffeine, which is a stimulant that increases caloric expenditure 11-14 and stimulates fat burning 13,15 and thereby weight loss 16, green coffee bean induces fat loss via non-stimulant mechanisms. First, green coffee bean slows down the absorption of glucose from the small intestine 17 and lowers after-meal blood glucose levels; the importance of this can be illustrated with the well documented effects seen with low glycemic index foods (enhanced fat burning, increased satiety and fat loss 18-21), which also slow down the absorption of glucose and lower blood glucose levels 22.
Second, green coffee bean inhibits carbohydrate digesting enzymes 23-26 and the actual absorption process itself 23,27. This means that less glucose gets taken up by the body, and thereby less calories.
Third, green coffee bean also shifts the site of glucose absorption to more distal parts of the intestine 17, which in turn enhances the secretion of the gut hormone GLP-1 (glucagon-like peptide 1). 28,29 This is an interesting effect in that GLP-1 currently is generating much scientific attention due to its involvement in satiety control, glucose homeostasis, and the cardiovascular system. The pharmaceutical industry is developing anti-diabetic drugs that act on GLP-1 to cause weight loss in overweight and obese patients 31, reduce blood pressure and improve endothelial function and vasodilatory effects 32. The GLP-1 weight loss effect has been attributed to a reduction in food intake and slowing of gastric emptying 33.
Fourth, chlorogenic acid in green coffee bean significantly inhibits fat synthesizing enzymes, while increasing the activity of fat burning enzymes 5.
Finally, as mentioned above, green coffee bean also increases blood levels of adiponectin 5,34, a hormone that is secreted from fat cells. Adiponectin enhances fat burning 35 and also
increases insulin sensitivity, lowers blood glucose (blood sugar) and reduces triglyceride levels 36-38.
Anti-diabetic - suppression of after-meal blood sugar spikes
Another major effect of green coffee bean is its ability to significantly lower fasting blood glucose levels 34, and especially dampen after-meal blood glucose surges 39,40. Why is this important and how many of us are affected?
35% of Americans aged 20 and older, and half of those aged 65 and older have pre-diabetes 41,42. The prevalence of undiagnosed diabetes is 27% 41. The high prevalence of pre-diabetes and undiagnosed diabetes is alarming since elevated fasting blood glucose levels even within the "normal" range greatly increase the risk for development of full-blown type 2 diabetes 43, stomach cancer 44, and heart attack 45. Fasting blood glucose values in the upper normal range are an important independent predictor of cardiovascular death even in non-diabetic apparently healthy people 46,47.
A mounting body of evidence shows that high after-meal blood glucose spikes inflict as much or even more damage than high fasting blood sugar 47-49. Among individuals with "normal" blood glucose readings, heart attack risk increases by 58% for a 21 mg/dl increase in after-meal blood sugar level 45, and 2 hour after-meal blood glucose levels are a strong determinant of atherosclerosis (diagnosed by IMT, intima-media-thickness) 50. It is well established that after-meal blood glucose spikes are an independent risk factor for heart attack and all-cause mortality 51. More specifically, people with the highest after-meal glucose levels, (range 150-194 mg/dL) have a 27% greater risk for cardiovascular disease compared with those with the lowest levels, (range 69-107 mg/dL 52.)
How effective is green coffee bean extract? In mice, green coffee bean extract was shown to dampen the elevation of blood glucose by 43% after a heavy meal 39. A notable study in humans tested different dosages of a standardized green coffee bean extract containing 50% chlorogenic acid 40. The subjects were given doses from 100 mg up to 400 mg and then ingested 100 g glucose (which is a standard method of testing of after-meal blood sugar elevations). It was found that after-meal blood glucose levels dropped by an increasingly greater amount as the dosage of the green coffee bean extract was raised 40. In the group of human subjects who took the 400 mg dose, there was a 24% drop in just 30 minutes after glucose ingestion, and a 32% drop after 2 hours 40. This means that if you had a dangerous after-meal glucose reading of 160 mg/dL, green coffee bean extract supplementation could slash it to 109 mg/dL, and thereby also markedly lower your health risk. It is not surprising that the anti-diabetic effect of coffee 53 has in large part been attributed to chlorogenic acid 54-56, and that it counteracts the negative effect of caffeine on glucose metabolism insulin sensitivity 57-62.
What determines your blood sugar levels?
While the amount of carbohydrates that you eat, coupled with how well your pancreas are working, have a significant effect on your blood sugar levels, this isn't the whole picture. There is an enzyme in the liver called glucose-6-phosphatase (G6P), which is a big player in the blood glucose equation. G6P releases glucose from stored glycogen in the liver into the bloodstream, and also converts protein to glucose 63,64. Among physically inactive people and those who tend to store body fat around the waist, the activity of G6P is elevated 65-71, which can throw your blood glucose levels off the chart. Stress also greatly ramps up G6P 66,72, and can wreak havoc with your blood glucose regulation.
It is here that chlorogenic acid comes to rescue; apart from inhibiting and slowing down the absorption of glucose, chlorogenic acid also inhibits the activity of G6P 73,74, which will help keep your blood glucose levels on track.According to the guidelines, your after-meal blood glucose should never exceed 140 mg/dL 75. If you want to test yourself, ask your doctor to give you a diabetes kit. Ideally, you want your after-meal blood level to be below 110 mg/dL. If it is higher than that, green coffee bean extract supplementation should be a supplement in your dietary regimen.